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    News: Brain Tumors

    Origins of neuroblastoma

    Monday, August 24th, 2015

    Neuroblastoma – a pediatric cancer of the sympathetic (“fight or flight”) nerve ganglia and adrenal glands – is thought to originate from the cells that give rise to the developing sympathetic nervous system. Amplification of the MYCN oncogene is associated with risk in this disease, but its role in the early steps of neuroblastoma initiation […]

    New type of trial shows promise for several cancers

    Monday, August 24th, 2015

    Anti-cancer drugs are typically tested on one type of cancer at a time. But an international consortium of cancer investigators, including Vanderbilt-Ingram Cancer Center (VICC) researchers, simultaneously tested an existing therapy in patients with several different forms of cancer that all exhibit the same tumor gene mutation. The new clinical trial showed promising results in […]

    Cancer signaling pathway blocker

    Friday, April 10th, 2015

    Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer. Abnormal regulation of this pathway leads to several human malignancies, including small cell lung cancer and pancreatic cancer, and therefore it is a potential drug target for cancer. Small molecules have […]

    NCI report shows U.S. cancer deaths on decline

    Thursday, April 2nd, 2015

    The death rates for most forms of cancer continue to decline at a modest pace among men, women and children in the United States, according to the Annual Report to the Nation on the Status of Cancer 1975 – 2011. The report from the National Cancer Institute, a division of the National Institutes of Health, […]

    New Method May Allow Personalized Clinical Trial for Cancer Therapies

    Tuesday, August 14th, 2012

    A new tool to observe cell behavior has revealed surprising clues about how cancer cells respond to therapy – and may offer a way to further refine personalized cancer treatments. The approach, developed by investigators at Vanderbilt-Ingram Cancer Center, shows that erlotinib – a targeted therapy that acts on a growth factor receptor mutated in […]

    Study Links Rare Genetic Marker to Brain Cancer

    Friday, August 10th, 2012

    Glioma is the most common and lethal type of brain tumor, and now investigators from Vanderbilt-Ingram Cancer Center and three other cancer centers have identified a link between a rare genetic variant and the risk of developing glioma. The variant also appears to improve the odds of survival among glioma patients. Reid Thompson, M.D., William […]

    Network Approach Yields Glioblastoma Clues

    Friday, August 10th, 2012

    MicroRNAs (miRNAs) play key roles in cellular development, differentiation and cancer growth by regulating gene expression. They may be clinically useful as biomarkers and as targets for new drugs to treat such cancers as glioblastoma multiforme, the most common and lethal primary brain tumor in humans. But first scientists must understand better how the actions […]

    Roots of Childhood Brain Tumors

    Wednesday, June 13th, 2012

    Identifying the cellular origins of medulloblastoma – the most common malignant brain tumor in children – may help focus treatment on cell types responsible for tumor initiation. Previous research has linked Sonic hedgehog signaling in neuronal cell precursors within the developing cerebellum to medulloblastoma. Now, Chin Chiang, Ph.D., and colleagues demonstrate that “turning on” Sonic […]

    Going for the Gold

    Tuesday, April 17th, 2012

    Vanderbilt-Ingram Cancer Center cordially invites you and your guests to join us for Going for the Gold: Living Well through Cancer! Due to an overwhelming response, we have closed registration. We are thrilled to have so many people attend! Date: Saturday, June 30, 2012 Time: 9:30 a.m.-2:30 p.m. Where: Vanderbilt University Student Life Center 310 […]

    Lymphedema Therapy

    Monday, December 19th, 2011

    Jadranko “Yadi” Franjic describes lymphedema symptoms and what is done during therapy to help control the swelling in the lymphatic system. Lymphedema is most common among patients who experience trauma to their lymphatic system. Examples include cancer patients undergoing lymphatic node dissection or radiation therapy and those who suffer a traumatic injury. Swelling of the […]

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