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    News: Breast Cancer

    Arteaga lauded for cancer research contributions

    Thursday, August 27th, 2015

    Carlos L. Arteaga, M.D., the Donna S. Hall Professor of Breast Cancer and director of the Center for Cancer Targeted Therapies and the Breast Cancer Program at Vanderbilt-Ingram Cancer Center (VICC), has been recognized for his cancer research efforts by the American-Italian Cancer Foundation (AICF). The AICF will also honor Frederick Alt, Ph.D., a Howard […]

    Study seeks to ease ‘chemobrain’ for cancer patients

    Monday, August 24th, 2015

    Many women who receive chemotherapy for breast cancer report problems with their thinking, memory and attention after treatment. And as the survival rates for breast cancer increase, so do these issues associated with chemotherapy. Paul Newhouse, M.D., professor of Psychiatry and Jim Turner Professor of Cognitive Disorders, and graduate student Jennifer Vega in Vanderbilt University […]

    New type of trial shows promise for several cancers

    Monday, August 24th, 2015

    Anti-cancer drugs are typically tested on one type of cancer at a time. But an international consortium of cancer investigators, including Vanderbilt-Ingram Cancer Center (VICC) researchers, simultaneously tested an existing therapy in patients with several different forms of cancer that all exhibit the same tumor gene mutation. The new clinical trial showed promising results in […]

    Study sheds light on crucial DNA binding protein

    Thursday, July 30th, 2015

    Researchers at Vanderbilt University have established the molecular basis for the function of Replication Protein A (RPA), a DNA binding protein that is a crucial “scaffold” for genome replication, response to damage and repair. With colleagues at Yale University, they also determined that the small, highly charged protein DSS1 acts on RPA to function as […]

    Exploring Accountable Care Organizations’ impact on cancer screenings

    Friday, May 29th, 2015

    As health care organizations implement new strategies to improve quality and reduce costs, a physician researcher at VUMC is setting out to identify whether there could be unintended effects. Matthew Resnick, M.D., MPH, assistant professor of Urologic Surgery and Health Policy, has been awarded a $726,000 grant from the American Cancer Society to study the […]

    Jansen’s cancer research efforts garner recognition

    Thursday, May 14th, 2015

    Valerie Malyvanh Jansen, M.D., Ph.D., a third-year medical oncology fellow, recently received several national awards and grants, as well as a Vanderbilt-Ingram Cancer Center fellowship, in recognition of her translational cancer research. Jansen received an American Association for Cancer Research (AACR) 2015 Women in Cancer Research Scholars Award. The awards are given to members of […]

    VICC research efforts in spotlight at AACR conference

    Thursday, April 30th, 2015

    Adding an investigational drug to an already approved estrogen blocking therapy appears to be safe and provided clinical benefit for some postmenopausal women with estrogen-positive breast cancer. The research led by Ingrid Mayer, M.D., associate professor of Medicine and clinical director of the Breast Cancer Program at Vanderbilt-Ingram Cancer Center (VICC), was selected for the […]

    Cancer signaling pathway blocker

    Friday, April 10th, 2015

    Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer. Abnormal regulation of this pathway leads to several human malignancies, including small cell lung cancer and pancreatic cancer, and therefore it is a potential drug target for cancer. Small molecules have […]

    Micelle “packets” deliver cancer drugs

    Friday, April 10th, 2015

    Small interfering RNA (siRNA) molecules can suppress tumor growth and target cells otherwise untreatable by conventional therapeutics, but targeted, intracellular delivery is a significant limitation to siRNA translation. To deliver the siRNA molecules into tumor cells, researchers have packaged them in micelles that express folic acid, which is internalized by cancer cells that overexpress folate […]

    NCI report shows U.S. cancer deaths on decline

    Thursday, April 2nd, 2015

    The death rates for most forms of cancer continue to decline at a modest pace among men, women and children in the United States, according to the Annual Report to the Nation on the Status of Cancer 1975 – 2011. The report from the National Cancer Institute, a division of the National Institutes of Health, […]

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