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    News: Cancer Research

    Coffey lands major NCI award to support colorectal cancer research

    Friday, June 9th, 2017

    Vanderbilt’s Robert Coffey Jr., M.D., has received an Outstanding Investigator Award from the National Cancer Institute (NCI) — more than $6.6 million over seven years — to support studies aimed at advancing the diagnosis and treatment of colorectal cancer (CRC), a leading cancer killer. Robert Coffey Jr., M.D. Coffey, Ingram Professor of Cancer Research and […]

    Project reveals importance of cancer gene mutation testing

    Friday, June 9th, 2017

    An international genomic data-sharing consortium has analyzed nearly 19,000 patient genomic records and found that testing of patient tumors for relevant gene mutations often provides a roadmap for the use of effective therapies. The American Association for Cancer Research (AACR) Genomics Evidence Neoplasia Information Exchange (GENIE) is a multi-phase, multi-year data-sharing project launched in 2015 […]

    Blood type link to cancer survival

    Friday, May 19th, 2017

    Ovarian cancer is the fifth leading cause of cancer deaths among women in the United States. Last year more than 14,000 deaths were reported. Despite treatment advances, overall five-year survival after diagnosis remains abysmally low at 45 percent. ABO blood type has been linked to multiple diseases including pancreatic and ovarian cancer risk. Two small […]

    Oxidative stress in tumors

    Friday, May 19th, 2017

    Reactive oxygen species (ROS) formed during the immune response help fight infections but ROS can also damage DNA and proteins by a process called peroxidation. The prolonged peroxidation of the lipid mediators of the inflammatory response by ROS results in the accumulation of small compounds called Isolevuglandins (IsoLGs), which can cause carcinogenic mutations leading to […]

    Glowing receptors help find and track cancerous growth

    Friday, May 19th, 2017

    Under the microscope, they sparkle like emeralds, these molecules that may hold a key to understanding — and stopping — cancerous growth. The molecules are protein receptors that bind epidermal growth factor (EGF). Overexpression of the EGF receptor has been linked to multiple types of cancer. Drugs that block the receptor have become routine treatment […]

    Researchers seek best ways to increase HPV vaccination rates

    Friday, May 12th, 2017

    Tennessee has one of the lowest human papillomavirus (HPV) vaccination rates in the nation, and investigators at Vanderbilt University Medical Center (VUMC) are hoping to change this by improving the way medical providers present these vaccines to patients and by improving patient and patient family education. “HPV is the most commonly sexually transmitted infection in […]

    Richmond to speak at national VA research conference on cancer immunotherapy

    Friday, May 12th, 2017

    Vanderbilt University cancer researcher Ann Richmond, Ph.D., 2016 recipient of one of the highest honors for scientific achievement bestowed by the U.S. Department of Veterans Affairs, will be a keynote speaker during a national VA research conference next week at Vanderbilt University School of Medicine. Ann Richmond, Ph.D. “Cancer Immunotherapy: Advances and Challenges” is the […]

    Top cancer researchers reveal latest findings at VICC science retreat

    Friday, May 12th, 2017

    Ordinary cells can be transformed into cancer cells through epigenetics — changes to DNA that turn genes on or off. Those gene changes can protect cells or make them vulnerable to disease processes including cancer. “Cancer Epigenetics — From Mechanisms to Therapies” was the topic of the Vanderbilt-Ingram Cancer Center (VICC) Annual Scientific Retreat held […]

    2016 Star Award recipients announced

    Tuesday, May 2nd, 2017

    The Vanderbilt-Ingram Cancer Center (VICC) Star Awards are awarded by VICC leadership annually to Cancer Center members to recognize their efforts and leadership among our researchers and clinicians in the following categories: Publications in High Impact Journals Accruals to Therapeutic Clinical Trials Accruals to Non-Therapeutic Clinical Trials For full list, see CY2016 Star Award Announcement  

    VUMC to Study Potential Approach to Reverse Precancerous Stomach Lesions

    Thursday, April 27th, 2017

    Vanderbilt University Medical Center (VUMC) cancer researcher James Goldenring, M.D., Ph.D., has received a two-year, $200,000 grant from the DeGregorio Family Foundation in Pleasantville, New York, to begin clinical trials of a potential approach for reversing precancerous stomach lesions. Stomach cancer is the fourth leading cause of cancer-related deaths worldwide after lung, liver and colorectal […]

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