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    News: Cancer Research

    Softening tumor tissue could aid cancer treatments

    Thursday, January 19th, 2017

    Normally, the glue that holds cells together in the human body – what scientists call the extracellular matrix – is soft and pliable. But when a metastatic tumor forms it causes the matrix surrounding it to stiffen. According to a new study, this mechanical effect produces changes in the blood vessels that feed the tumor […]

    VICC joins cancer genomic data sharing initiative

    Thursday, January 19th, 2017

    Vanderbilt-Ingram Cancer Center (VICC) has joined an international consortium of leading cancer centers to share genomic data from patients in an effort to accelerate the pace of cancer research and improve precision medicine. That consortium has now released 19,000 de-identified genomic and partial clinical records collected from patients who were treated at eight international institutions […]

    Metastatic pancreatic cancer ‘reprograms’ for malignancy

    Thursday, January 19th, 2017

    Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics. It may be possible to reverse the malignant reprogramming to treat metastatic pancreatic cancer, […]

    Vanderbilt-Ingram Cancer Center Supports National HPV Vaccination Efforts

    Tuesday, January 17th, 2017

    Nearly 39,000 new cancers associated with the human papillomavirus (HPV) will be diagnosed in the United States this year. Although HPV vaccines can prevent the majority of these cancers, vaccination rates remain low across the country. Recognizing a critical need to improve national vaccination rates for HPV, Vanderbilt-Ingram Cancer Center (VICC) is again uniting with […]

    Midgut neuroendocrine tumor prognosis

    Thursday, January 12th, 2017

    Patients with small intestine neuroendocrine tumors often have mesenteric tumor deposits (MTDs) in the abdomen – discrete tumor nodules that are not connected to the primary tumor. The clinical significance of these tumor deposits has not been thoroughly investigated, and they are not included in the American Joint Committee on Cancer (AJCC) staging system for […]

    Team’s discovery offers new insight on lung cancer risk

    Thursday, January 12th, 2017

    Researchers in the Schools of Medicine and Engineering at Vanderbilt University have discovered a proteomic “signature” from the airways of heavy smokers that could lead to better risk assessment and perhaps new ways to stop lung cancer before it starts. Their findings, reported recently in the journal JCI Insight, are based on the observation that […]

    Acting NCI director Lowy to present HPV research lecture

    Thursday, January 12th, 2017

    Douglas R. Lowy, acting director of the National Cancer Institute, will deliver the Vanderbilt-Ingram Cancer Center George Daniel Brooks Lecture at Vanderbilt University Medical Center on Tuesday, Jan. 24, at 11 a.m. in Light Hall, Room 208. The title of the presentation is “Preventing HPV-associated Cancers: Short-term and Long-term Approaches.” Lowy is chief of the […]

    Study to explore lymphedema self care for cancer survivors

    Thursday, December 15th, 2016

    Vanderbilt University School of Nursing (VUSN) Assistant Professor Jie Deng, Ph.D., R.N., has been awarded a $789,000 research scholar grant by the American Cancer Society to develop and test a self-care program for head and neck cancer survivors diagnosed with secondary lymphedema and fibrosis (LEF). LEF causes swelling and the development of hard tissue in […]

    Ozgener family responds to cancer by supporting research

    Thursday, December 15th, 2016

    Nashville entrepreneur-turned-artist Cano Ozgener and his family have repeatedly faced cancer and its consequences, but rather than feel embattled, they’ve chosen to respond by creating beauty to share with others and by actively supporting the mission of the Vanderbilt-Ingram Cancer Center (VICC). Ozgener and his wife, Esen, established the Esen and Cano Ozgener Research Fund […]

    Protecting the blood-brain barrier

    Wednesday, December 14th, 2016

    Interleukin 2 (IL2) is the first effective immunotherapy approved to treat human cancers. But IL2 also disrupts the blood-brain barrier, causing brain edema due to vascular leak syndrome, which limits its use. How IL2 affects brain cells is not currently known. Now, in a paper published in the Journal of Biological Chemistry, graduate student Lukasz […]

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