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    News: Cancer Research

    New software tracks cancer mutations, survival

    Thursday, June 2nd, 2016

    Malignant tumors are increasingly subject to routine clinical genotyping, primarily to predict drug response or assist with prognosis. A team at Vanderbilt University Medical Center (VUMC) has developed and tested software that scans electronic health records in real time to monitor cancer patient survival (from time of diagnosis) according to which genes, if any, are […]

    Precision medicine already changing cancer treatment strategies

    Thursday, May 26th, 2016

    The ability to test patients’ cancers for individual differences, mainly at the genetic level, and to make treatment decisions based on those differences is the hallmark of precision medicine, and Vanderbilt University Medical Center (VUMC) is among the leaders of this new approach to diagnosis and treatment. “Nationwide we’re seeing great promise with this approach […]

    Students’ cancer research efforts land honors

    Thursday, May 19th, 2016

    Two Vanderbilt students were recognized for their contributions to cancer research during the Vanderbilt-Ingram Cancer Center (VICC) Annual Scientific Retreat held May 6 at the Vanderbilt University Student Life Center. Huzefa Dungrawala, Ph.D., was named VICC Postdoctoral Student of the Year for his outstanding research in the laboratory of David Cortez, Ph.D., Ingram Professor of […]

    VICC investigators in spotlight at AACR conference

    Thursday, May 19th, 2016

    A top Vanderbilt-Ingram Cancer Center (VICC) investigator recently met with Vice President Joe Biden regarding the National Cancer Moonshot Initiative, a major national program to identify, fund and accelerate the most promising research leading to cancer cures. Carlos L. Arteaga, M.D., director of the Center for Cancer Targeted Therapies and the VICC Breast Cancer Program, […]

    Endowed fellowships help create personal connections

    Monday, May 16th, 2016

    When former Nashvillian Carol O’Hare speaks about a specific group of physicians at Vanderbilt-Ingram Cancer Center (VICC), her voice softens, and she refers to them affectionately as “my fellows.” O’Hare, a 19-year cancer survivor who received life-saving treatment at VICC and whose late husband was also treated for cancer here, decided to support oncology research […]

    Improving natural killer cancer therapy

    Friday, May 6th, 2016

    Natural Killer (NK) cells are a type of white blood cell that specifically recognize and destroy tumor cells. For this reason, NK cell transfer therapy is a promising cancer treatment. Expansion and persistence of donor NK cells correlates with tumor clearance, suggesting that therapeutic efficacy can be enhanced by augmenting NK cell survival. Now, Whitney […]

    Current cancer drug discovery method flawed: VUMC study

    Friday, May 6th, 2016

    The primary method used to test compounds for anti-cancer activity in cells is flawed, Vanderbilt University researchers reported May 2 in Nature Methods. The findings cast doubt on methods used by the entire scientific enterprise and pharmaceutical industry to discover new cancer drugs. “More than 90 percent of candidate cancer drugs fail in late-stage clinical […]

    Zanic’s research recognized with 2016 Searle Scholarship

    Friday, April 29th, 2016

    An expert in the dynamic behavior of the microtubule cytoskeleton at Vanderbilt University is among 15 scientists in the chemical and biological sciences nationwide who have been named 2016 Searle Scholars. Marija Zanic, Ph.D., assistant professor of Cell and Developmental Biology and of Chemical and Biomolecular Engineering, will receive $300,000 in flexible funding from the […]

    An Argonaute’s voyage to cancer

    Friday, April 29th, 2016

    Mutations in the KRAS gene, which codes for a protein involved in normal cell signaling, promote the development of colorectal and other cancers. One mechanism by which activated KRAS may influence the phenotype of neighboring cells is by regulating the packaging of tiny RNAs called microRNAs (miRNAs) in small, bubble-like vesicles called exosomes. When delivered […]

    Study explores how some breast cancers resist treatment

    Thursday, April 21st, 2016

    A targeted therapy for triple-negative breast cancer (TNBC), the most aggressive form of breast cancer, has shown potential promise in a recently published study. TNBC is the only type of breast cancer for which there are no currently approved targeted therapies. The new study led by Vanderbilt-Ingram Cancer Center (VICC) investigators has identified gene alterations […]

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