A new study by Dai Chung, MD, and colleagues reports that a protein, called SIRT6, plays an important role in the growth of neuroblastoma and suggests that SIRT6 may be a target for new therapeutics for the disease.
News: Childhood Cancer
The Vanderbilt-Ingram Cancer Center Neurofibromatosis (NF) Clinic has joined the Children’s Tumor Foundation NF Clinic Network. The network consists of 50 clinics dedicated to improving care and advancing research for people diagnosed with NF, a group of diseases that is often inherited and cause benign tumors to grow on nerves throughout the body.
Nashville Predators goaltender Pekka Rinne, Predators executive leaders, executives from Tri Star Energy (Twice Daily) and team mascot Gnash recently presented the proceeds of the team’s 365 Pediatric Cancer Fund to Monroe Carell Jr. Children’s Hospital at Vanderbilt.
A recent study by Dai Chung, M.D., and colleagues suggests new therapeutic options for Ewing sarcoma, a type of rare, aggressive childhood cancer.
Adam Esbenshade, M.D., MSCI, assistant professor of Pediatrics in the Division of Pediatric Hematology/Oncology, has been awarded a $50,000 Hyundai Hope on Wheels Impact Award. Esbenshade plans to use data to create a risk prediction model to predict blood stream infections in pediatric cancer patients. The grant was celebrated in a “handprint ceremony” on Aug. […]
A grant from cancer research nonprofit Alex’s Lemonade Stand Foundation is allowing a Vanderbilt chemical and biomolecular engineering doctoral student to join the fight against pediatric neuroblastoma. Kyle Garland is spending his summer on a project titled Immunotherapeutic Targeting of the STING Pathway to Combat Neuroblastoma. He’s working with John Wilson, assistant professor of chemical […]
Neuroblastoma – a cancer that starts in nerve tissue outside of the brain – is the third most common cancer in children and accounts for about 15 percent of pediatric cancer-related deaths. MYC proteins drive neuroblastoma tumorigenesis in part by promoting the expression of key glycolytic enzymes such as LDHA to induce aerobic glycolysis (a […]
Finn Schafran has always been a happy child, but these days the nearly 2-year-old boy is adjusting to spending part of each day at Vanderbilt-Ingram Cancer Center (VICC), where he receives chemotherapy and radiation for a rare cancer. Finn’s parents sought treatment when they realized their son was having pain and then developed a bulge […]
Richard Ho, M.D., MSCI, associate professor of Pediatrics in the Division of Pediatric Hematology/Oncology, has been awarded a $250,000 Hyundai Hope On Wheels Scholar Grant to study ways to reduce long-term side effects of chemotherapy in pediatric cancer survivors and develop more personalized therapies for pediatric oncology patients. To date, Hyundai Hope On Wheels has […]
Neuroblastoma is a neural crest cell-derived extracranial solid cancer that affects infants and young children. The most vigorous of these cancers spreads through self-renewing cancer stem cells. Knowing the nature of these cells is essential to understanding the progression of neuroblastoma and devising the right treatment strategy. Reporting in the journal Biochemical and Biophysical Research […]