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News: Colorectal Cancer

Brown to head cancer registry for Y-90 tumor treatments

Thursday, July 30th, 2015

Dan Brown, M.D., professor of Radiology and Radiological Sciences and chief of Interventional Oncology, will spearhead a national Vanderbilt-led research registry that tracks cancer patients whose tumors are treated with Yttrium-90 (Y-90), a radioactive isotope. The Radiation-Emitting SIR-Spheres in Non-Resectable (RESIN) Liver Tumor Patient Registry is the result of a collaboration between VUMC, initially up […]

Study explores protein’s role in inflammation-associated cancer

Thursday, July 23rd, 2015

A protein that transports the micronutrient selenium and has antioxidant functions may protect against colitis-associated carcinoma — colon cancer that develops in patients with inflammatory bowel disease, according to a new Vanderbilt-led study. The findings, reported in the July issue of the Journal of Clinical Investigation, could suggest strategies for reducing colon cancer risk in […]

Exploring Accountable Care Organizations’ impact on cancer screenings

Friday, May 29th, 2015

As health care organizations implement new strategies to improve quality and reduce costs, a physician researcher at VUMC is setting out to identify whether there could be unintended effects. Matthew Resnick, M.D., MPH, assistant professor of Urologic Surgery and Health Policy, has been awarded a $726,000 grant from the American Cancer Society to study the […]

Tools for exploring ‘omics’ data

Thursday, May 21st, 2015

Advances in technology have generated vast amounts of “omics” data: genomic, epigenomic, transcriptomic, proteomic and metabolomic changes for all types of specimens. Bridging the gap between data generation and investigators’ ability to retrieve and interpret data is essential to realize the biological and clinical value of this wealth of information. Bing Zhang, Ph.D., and colleagues […]

American Surgical Association lauds VUMC’s Beauchamp

Thursday, May 14th, 2015

R. Daniel Beauchamp, M.D., chair of the Section of Surgical Sciences and the John Clinton Foshee Distinguished Professor of Surgery, was selected to receive the 2015 Flance-Karl Award from the American Surgical Association (ASA). Beauchamp, who is also a professor of Surgery, Cancer Biology and Cell and Developmental Biology, traveled to San Diego last week […]

Kachnic to join VUMC as new chair of Radiation Oncology

Thursday, May 7th, 2015

Lisa Kachnic, M.D., professor and chair of Radiation Oncology and associate director of Multidisciplinary Cancer Research at Boston University School of Medicine (BUSM), and chief of Radiation Oncology at Boston Medical Center (BMC), has been named the new professor and chair of the Vanderbilt Department of Radiation Oncology. She will join the faculty on Sept. […]

Best hospital depends on cancer type

Thursday, April 23rd, 2015

The idea of a “Best Hospital for Cancer” does not reflect the fact that cancer comprises many different diseases. Jeffery Goldstein, M.D., Ph.D., a resident in the Department of Pathology, Microbiology and Immunology at Vanderbilt, and Vinay Prasad, M.D., MPH, aimed to rank the 50 highest ranked cancer hospitals – from the 2013 U.S. News […]

NCI report shows U.S. cancer deaths on decline

Thursday, April 2nd, 2015

The death rates for most forms of cancer continue to decline at a modest pace among men, women and children in the United States, according to the Annual Report to the Nation on the Status of Cancer 1975 – 2011. The report from the National Cancer Institute, a division of the National Institutes of Health, […]

Gene profile predicts metastasis

Thursday, February 12th, 2015

Gene expression profiling has been applied to predict metastatic recurrence, the leading cause of deaths in patients with colorectal carcinoma. However, the biological mechanism is not completely understood, driving poor clinical outcomes. To address this issue, Dan Beauchamp, M.D., Bing Zhang, Ph.D., and colleagues analyzed the 11 human microarray datasets from 1,295 tumor specimens as […]

Protein “pockets” help ID cancer genes

Tuesday, November 11th, 2014

Somatic mutations, which can occur in any cell except sperm or egg, are not inheritable. Several recent studies have demonstrated that disease-causing mutations commonly alter protein folding, protein stability and protein-protein interactions. It has been difficult, however, to determine which somatic mutations identified in tumor samples “drive” the cancer development and which are just “along […]

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