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    News: Gastrointestinal Cancer

    New target for chronic infection

    Thursday, February 2nd, 2017

    The greatest risk factor for gastric cancer is chronic infection by the bacterium, Helicobacter pylori. In a study in mice published by the Proceedings of the National Academy of Sciences, Dana Hardbower, Keith Wilson, M.D., and colleagues found that macrophage activation has a critical role in regulating H. pylori colonization and gastric inflammation. Macrophages are […]

    Metastatic pancreatic cancer ‘reprograms’ for malignancy

    Thursday, January 19th, 2017

    Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics. It may be possible to reverse the malignant reprogramming to treat metastatic pancreatic cancer, […]

    Midgut neuroendocrine tumor prognosis

    Thursday, January 12th, 2017

    Patients with small intestine neuroendocrine tumors often have mesenteric tumor deposits (MTDs) in the abdomen – discrete tumor nodules that are not connected to the primary tumor. The clinical significance of these tumor deposits has not been thoroughly investigated, and they are not included in the American Joint Committee on Cancer (AJCC) staging system for […]

    Study links lifestyle factors to formation of high-risk polyps

    Thursday, December 8th, 2016

    Lifestyle factors like cigarette smoking and red meat consumption are known to be associated with an increased risk of colon polyps that can lead to colorectal cancer. Polyps are small growths on the lining of the colon, and while some polyps are harmless others can progress to cancer. A new study led by Vanderbilt University […]

    EGF receptor found to regulate macrophage inflammation in gut

    Thursday, October 13th, 2016

    Researchers at Vanderbilt University School of Medicine have uncovered a link between epidermal growth factor receptor (EGFR) signaling and the inflammatory response to bacterial infection in the gastrointestinal tract. In particular, they have found — in mice and human tissue — that EGFR signaling regulates the response of an inflammatory macrophage (a type of white […]

    Colon cancer awareness event set for Aug. 5

    Thursday, July 28th, 2016

    For some people cancer, especially colon cancer, is a persistent and potentially deadly visitor affecting family members from one generation to the next. Individuals who have a parent, sibling or child diagnosed with colon cancer have double the risk of developing the disease. But not all colon cancer is caused by hereditary factors. Vanderbilt-Ingram Cancer […]

    Idrees receives award for cancer outcomes research

    Thursday, July 7th, 2016

    Kamran Idrees, M.D., MSCI, assistant professor of Surgery, has received a Young Investigator Award from the Society of Surgical Oncology Foundation (SSO). The award supports innovative concepts designed to improve health outcomes through advances in the delivery of care. Idrees, who joined the Vanderbilt faculty in 2012, said the one-year award “was an unexpected honor […]

    Goldenring recognized for research mentorship efforts

    Thursday, June 23rd, 2016

    James Goldenring, M.D., Ph.D., co-director of the Epithelial Biology Center at Vanderbilt University Medical Center (VUMC), has received a Research Mentor Award from the American Gastroenterology Association Institute Council for “outstanding research mentorship.” Goldenring is the Paul W. Sanger Professor of Experimental Surgery and professor of Cell and Developmental Biology and vice chair of Surgical […]

    Patient encourages early screening for colon cancer

    Friday, April 1st, 2016

    Van Edmundson, a retiree from Ashland City, Tennessee, had his first screening colonoscopy at 50, the age recommended for most patients. Individuals with a family history of colorectal cancer or with current gastrointestinal symptoms may need to be screened earlier. Edmundson’s test was negative for colon cancer and he got the all-clear again when he […]

    Singer’s concert honors care received at Cancer Center

    Thursday, March 24th, 2016

    A cancer patient’s gratitude toward his Vanderbilt-Ingram Cancer Center (VICC) physician led to a star-studded concert to benefit the Cancer Center. Colon cancer survivor and country artist Wade Hayes was joined by six-time CMA and ACM Female Vocalist of the Year Miranda Lambert, four-time Grammy and CMA Award-winning artist Steve Wariner and Kix Brooks, CMA […]

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