Skip to Content
 

E-Newsletter

  • Subscribe to our e-Newsletter to receive email updates:

  • Related Articles

    Most Recent

    Archives

    Join Us

    News: Gastrointestinal Cancer

    New tools help surgeons find liver tumors, not nick blood vessels

    Friday, July 21st, 2017

    The liver is a particularly squishy, slippery organ, prone to shifting both deadly tumors and life-preserving blood vessels by inches between the time they’re discovered on a CT scan and when the patient is lying on an operating room table. Surgeons can swab the exposed liver lightly on the surface with a special stylus, capturing the shape of […]

    Kachnic named one of the ‘Women to Watch’ in health care

    Thursday, July 13th, 2017

    Lisa Kachnic, M.D., Cornelius Vanderbilt Chair in Radiation Oncology and chair of the Department of Radiation Oncology at Vanderbilt University Medical Center (VUMC), has been named one of the “Women to Watch” in health care by Nashville Medical News. Lisa Kachnic, M.D. Kachnic is among 10 women in the Class of 2017 recognized by the health […]

    Bile acids, microbiota and colon cancer

    Monday, July 10th, 2017

    Deoxycholic acid (DCA), a secondary bile acid that is increased by high dietary fat intake – a western diet – has been linked to intestinal carcinogenesis. In a previous study, Fang Yan, M.D., Ph.D., and colleagues showed that DCA accelerated the progression of adenoma to adenocarcinoma in mice that spontaneously develop intestinal adenomas. Now, the researchers […]

    Coffey lands major NCI award to support colorectal cancer research

    Friday, June 9th, 2017

    Vanderbilt’s Robert Coffey Jr., M.D., has received an Outstanding Investigator Award from the National Cancer Institute (NCI) — more than $6.6 million over seven years — to support studies aimed at advancing the diagnosis and treatment of colorectal cancer (CRC), a leading cancer killer. Robert Coffey Jr., M.D. Coffey, Ingram Professor of Cancer Research and […]

    Glowing receptors help find and track cancerous growth

    Friday, May 19th, 2017

    Under the microscope, they sparkle like emeralds, these molecules that may hold a key to understanding — and stopping — cancerous growth. The molecules are protein receptors that bind epidermal growth factor (EGF). Overexpression of the EGF receptor has been linked to multiple types of cancer. Drugs that block the receptor have become routine treatment […]

    VUMC to Study Potential Approach to Reverse Precancerous Stomach Lesions

    Thursday, April 27th, 2017

    Vanderbilt University Medical Center (VUMC) cancer researcher James Goldenring, M.D., Ph.D., has received a two-year, $200,000 grant from the DeGregorio Family Foundation in Pleasantville, New York, to begin clinical trials of a potential approach for reversing precancerous stomach lesions. Stomach cancer is the fourth leading cause of cancer-related deaths worldwide after lung, liver and colorectal […]

    Study takes 3-D perspective on colorectal cancer

    Friday, March 24th, 2017

    Despite dramatic recent advances in treatment, colorectal cancer killed more than 49,000 Americans last year, according to the National Cancer Institute, making it the second most lethal malignancy after cancers of the lung and bronchus. Determined to reduce the death toll, researchers at Vanderbilt University Medical Center recently put on their 3-D “glasses” and took […]

    Improving therapies for GI tumors

    Thursday, February 23rd, 2017

    The signaling protein Aurora kinase A (AURKA) is overexpressed in several cancer types and has diverse oncogenic functions, making it an attractive druggable cancer target. Wael El-Rifai, M.D., Ph.D., and colleagues are exploring a role for AURKA in upper gastrointestinal cancers, which are characterized by poor patient survival and resistance to chemotherapy. Using in vitro […]

    New target for chronic infection

    Thursday, February 2nd, 2017

    The greatest risk factor for gastric cancer is chronic infection by the bacterium, Helicobacter pylori. In a study in mice published by the Proceedings of the National Academy of Sciences, Dana Hardbower, Keith Wilson, M.D., and colleagues found that macrophage activation has a critical role in regulating H. pylori colonization and gastric inflammation. Macrophages are […]

    Metastatic pancreatic cancer ‘reprograms’ for malignancy

    Thursday, January 19th, 2017

    Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics. It may be possible to reverse the malignant reprogramming to treat metastatic pancreatic cancer, […]

    Next Page »

    E-Newsletter

  • Subscribe to our e-Newsletter to receive email updates:

  • Related Articles

    Most Recent

    Archives

    Join Us