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News: Gastrointestinal Cancer Research Program

Cancer prevention drug also disables H. pylori bacterium

Thursday, April 4th, 2019

Vanderbilt investigators report that a medicine currently being tested as a chemoprevention agent for multiple types of cancer can also act directly reduce the virulence of Helicobacter pylori, the primary cause of gastric cancer.

Protein loss promotes cell migration

Monday, March 4th, 2019

The protein STK17A (serine threonine kinase 17A) appears to play roles in various cancer types. Researchers have found that cells without STK17A become less connected and more invasive.

Probing H. pylori cancer protein

Thursday, February 14th, 2019

A new study improves the understanding of how the stomach-dwelling bacterium Helicobacter pylori influences the risk of premalignant and malignant changes in the stomach.

Major grant to bolster research on inflammation-related cancers

Thursday, January 24th, 2019

Cancer Research UK has awarded a 20-million-pound grant (about $26 million U.S.) to a team of international investigators, including Vanderbilt’s James Goldenring, MD, PhD, to study inflammation-related cancers.

Cancer Moonshot award to help map tumor progression

Thursday, September 27th, 2018

A trans-institutional team of researchers at Vanderbilt University Medical Center and Vanderbilt University has received an $11 million Cancer Moonshot grant to build a single-cell resolution atlas to map out the routes that benign colonic polyps take to progress to colorectal cancer.

Diabetes drug may prevent cancer

Friday, September 21st, 2018

A drug commonly used to treat type 2 diabetes might help prevent patients from developing liver cancers, according to a recent study by Harvey J. Murff, MD, MPH, and colleagues.

SMAD4 clue to colon cancer

Friday, July 6th, 2018

A recent study has linked inflammation-driven carcinogenesis in the colon to loss of an important signaling protein called SMAD4.

Agreement renewal bolsters liver tumor research

Friday, April 13th, 2018

Sirtex Medical Ltd. has renewed a grant award to Dan Brown, MD, professor of Radiology and Radiological Sciences and chief of Interventional Oncology, and his Vanderbilt Health colleagues, for a research program designed to treat patients with liver tumors that cannot be addressed with surgery.

Peek named to serve on NIDDK Advisory Council

Thursday, March 22nd, 2018

Richard Peek, MD, director of the Vanderbilt Digestive Disease Research Center (VDDRC) and chief of the Division of Gastroenterology, Hepatology and Nutrition, has been appointed to serve on the advisory council of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

VUMC researchers find a way to ‘starve’ cancer

Thursday, January 18th, 2018

Researchers at Vanderbilt University Medical Center (VUMC) have demonstrated for the first time that it is possible to starve a tumor and stop its growth with a newly discovered small compound that blocks uptake of the vital nutrient glutamine.

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