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News: Gastrointestinal Cancer Research Program

Cellular soldiers designed to kill cancer cells that get loose during surgery, stop metastasis

Friday, July 26th, 2019

Cellular soldiers created using the body’s own defenses can track down and kill escaping cancer cells during surgeries, preventing metastasis and saving lives, a Vanderbilt University biomedical engineer has discovered, particularly in cases of triple negative breast cancer.

Vanderbilt team shows how stomach bug can trigger cancer

Thursday, July 11th, 2019

Researchers have obtained the first high-resolution image of a molecular “machine” used by the insidious stomach bug Helicobacter pylori to inject a cancer-causing protein into the stomach lining.

Fish oil and cancer prevention

Saturday, June 29th, 2019

Fish oil supplementation provides a modest but beneficial effect on reducing molecules associated with colorectal cancer development.

Eng named to GI cancer leadership position at VICC

Saturday, June 29th, 2019

Cathy Eng, MD, a national and international leader in gastrointestinal medical oncology, is joining Vanderbilt-Ingram Cancer Center (VICC).

Receptor’s role in stopping H. pylori

Thursday, April 25th, 2019

A recent study demonstrates that loss of the receptor NOD1 augments inflammatory and injury responses to H. pylori – and points towards NOD1 as a prime target for modification for either preventing or treating H. pylori infections.

Discovery aids search for cancer biomarkers

Thursday, April 25th, 2019

A report by researchers at Vanderbilt University Medical Center has shattered conventional wisdom about how cells, including cancer cells, shed DNA into the bloodstream: they don’t do it by packaging the genetic material in tiny vesicles called exosomes.

Cancer prevention drug also disables H. pylori bacterium

Thursday, April 4th, 2019

Vanderbilt investigators report that a medicine currently being tested as a chemoprevention agent for multiple types of cancer can also act directly reduce the virulence of Helicobacter pylori, the primary cause of gastric cancer.

Protein loss promotes cell migration

Monday, March 4th, 2019

The protein STK17A (serine threonine kinase 17A) appears to play roles in various cancer types. Researchers have found that cells without STK17A become less connected and more invasive.

Probing H. pylori cancer protein

Thursday, February 14th, 2019

A new study improves the understanding of how the stomach-dwelling bacterium Helicobacter pylori influences the risk of premalignant and malignant changes in the stomach.

Major grant to bolster research on inflammation-related cancers

Thursday, January 24th, 2019

Cancer Research UK has awarded a 20-million-pound grant (about $26 million U.S.) to a team of international investigators, including Vanderbilt’s James Goldenring, MD, PhD, to study inflammation-related cancers.

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