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News: Genome Maintenance Research Program

Understanding cell division

Monday, November 18th, 2019

Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells.

Rathmell receives 2019 Eugene P. Schonfeld Award

Wednesday, November 6th, 2019

The Kidney Cancer Association is recognizing the research accomplishments and leadership achievements of W. Kimryn Rathmell, MD, PhD, with its top honor, the Eugene P. Schonfeld Award.

Completing DNA synthesis

Monday, October 21st, 2019

James Dewar and colleagues have identified a role for the enzyme topoisomerase II in reducing replication errors during the final stage of DNA synthesis.

VICC’s Rathmell honored with Louisa Nelson Award

Thursday, October 3rd, 2019

Kimryn Rathmell, MD, PhD, director of the Division of Hematology and Oncology, received an award that honors women who embody the achievement, vision and inspiration of the founder of a local distillery.

Team’s study reveals details of new DNA repair pathway

Friday, July 26th, 2019

Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity.

International Association of Medical Science Educators honors Osheroff

Thursday, July 11th, 2019

Neil Osheroff, PhD, received the Distinguished Career Award for Excellence in Teaching and Educational Scholarship from the International Association of Medical Science Educators (IAMSE).

Potential probe for early ovarian cancer

Saturday, June 29th, 2019

Larry Marnett and colleagues have developed what may become the first agent for targeted PET imaging of cancer tissues, such as ovarian cancer, that express high levels of the COX-1 enzyme.

Steroid binding to metabolic enzyme

Saturday, June 29th, 2019

Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer.

Researchers putting the brakes on lethal childhood cancer

Friday, May 3rd, 2019

A recent study suggests that blocking the MYC protein could be “unexpectedly effective” in treating malignant rhabdoid tumor (MRT) is one of the most aggressive and lethal childhood cancers.

Correctly copying DNA

Friday, March 15th, 2019

A precise understanding of how the enzyme topoisomerase II cuts DNA could lead to better anti-cancer therapies.

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