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News: Host-Tumor Interactions Research Program

Vanderbilt Biophotonics Center collaboration seeks earlier diagnosis of throat cancer

Saturday, December 1st, 2018

Researchers in the schools of engineering and medicine are exploring the use of Raman spectroscopy for early detection of HPV-related cancers of the throat in order to reduce the need for biopsies and to offer less intensive therapies.

Team’s findings show glutamine metabolism affects T cell signaling

Monday, November 5th, 2018

A drug currently in clinical trials as an anticancer agent might also be useful as a treatment for inflammatory and autoimmune diseases. The findings also suggests strategies for using the drug to enhance cancer immunotherapies.

Karijolich named 2018 Pew Biomedical Scholar

Friday, June 15th, 2018

John Karijolich, PhD, a member of the cancer center’s Host-Tumor Interactions Research Program, has been named a Pew Biomedical Scholar by The Pew Charitable Trusts. His laboratory investigates viruses associated with human cancer.

$8.1 million grant funds new center to research highly aggressive form of lung cancer

Tuesday, June 12th, 2018

The grant from the National Cancer Institute, establishes a research center for advancing the understanding and treatment of small cell lung cancer. Vito Quaranta, M.D., will direct the new center.

“Idling” cancer cells may return

Friday, April 13th, 2018

Vito Quaranta, MD, and colleagues have found that treated melanoma cells enter a previously unrecognized “idling” state. These idling cells may be primed to acquire resistance mutations and may constitute the bulk of residual disease.

Peek named to serve on NIDDK Advisory Council

Thursday, March 22nd, 2018

Richard Peek, MD, director of the Vanderbilt Digestive Disease Research Center (VDDRC) and chief of the Division of Gastroenterology, Hepatology and Nutrition, has been appointed to serve on the advisory council of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Young named chief medical officer of American Red Cross

Thursday, January 4th, 2018

Vanderbilt’s Pampee Young, MD, PhD, has been named chief medical officer of the American Red Cross.

Immune responses linked to cell’s recycling system

Friday, July 21st, 2017

Autophagy is the cellular equivalent of trash pickup and recycling — it is a process by which proteins, protein aggregates and damaged cellular organelles are degraded in order to reuse nutrients and promote cellular metabolism. Now researchers at Vanderbilt University Medical Center have found that autophagy also plays an important role in priming the body’s […]

Nanobeacon lights up colon tumors

Sunday, April 2nd, 2017

The advent of colorectal cancer (CRC) screening, notably colonoscopy, has reduced deaths from this common and deadly malignancy by 30 percent. Unfortunately, colonoscopy misses about 24 percent of small and flat polyps, which often develop into aggressive forms of CRC. Now Wellington Pham, Ph.D., and colleagues report that a novel fluorescent nanobeacon can discern normal […]

Links between immune cells and metabolism explored

Thursday, November 10th, 2016

At the intersection of immunology and metabolism is a burgeoning new field: immunometabolism. It’s an area where Vanderbilt has exceptional strengths, said Jeffrey Rathmell, Ph.D., Cornelius Vanderbilt Professor of Immunobiology. “It’s an unsung area of expertise here,” said Rathmell, who is also professor of Pathology, Microbiology and Immunology and professor of Cancer Biology. “There are […]

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