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News: Host-Tumor Interactions Research Program

Receptor’s role in stopping H. pylori

Thursday, April 25th, 2019

A recent study demonstrates that loss of the receptor NOD1 augments inflammatory and injury responses to H. pylori – and points towards NOD1 as a prime target for modification for either preventing or treating H. pylori infections.

Lighting up colorectal cancer

Monday, March 4th, 2019

Wellington Pham, PhD, and colleagues in Japan, have developed a nanobeacon imaging agent to aid the early detection of colorectal cancer during colonoscopy.

Grant supports novel imaging initiative to enhance cancer care

Monday, February 4th, 2019

A Vanderbilt initiative to develop predictive imaging technologies that clinicians can use to better match patients with personalized care has received National Cancer Institute (NCI) funding.

Research team documents potential new treatment path for breast cancer

Friday, January 18th, 2019

Immunotherapies that take off the “brakes” on the adaptive anti-tumor response have worked well in melanoma and lung cancer but less so in breast cancers. That could change.

RNA processing and antiviral immunity

Friday, December 14th, 2018

A recent study in Nature Communications defines the in vivo substrates of RIG-I like receptors (RLRs) during an oncogenic virus infection and reveals a relationship between cellular RNA processing and an innate antiviral immune response.

Philip’s liver cancer research receives V Foundation support

Friday, December 14th, 2018

Mary Philip, MD, PhD, has been named a 2019 V Scholar and will receive $200,000 from the V Foundation for Cancer Research.

Vanderbilt Biophotonics Center collaboration seeks earlier diagnosis of throat cancer

Saturday, December 1st, 2018

Researchers in the schools of engineering and medicine are exploring the use of Raman spectroscopy for early detection of HPV-related cancers of the throat in order to reduce the need for biopsies and to offer less intensive therapies.

Team’s findings show glutamine metabolism affects T cell signaling

Monday, November 5th, 2018

A drug currently in clinical trials as an anticancer agent might also be useful as a treatment for inflammatory and autoimmune diseases. The findings also suggests strategies for using the drug to enhance cancer immunotherapies.

Karijolich named 2018 Pew Biomedical Scholar

Friday, June 15th, 2018

John Karijolich, PhD, a member of the cancer center’s Host-Tumor Interactions Research Program, has been named a Pew Biomedical Scholar by The Pew Charitable Trusts. His laboratory investigates viruses associated with human cancer.

$8.1 million grant funds new center to research highly aggressive form of lung cancer

Tuesday, June 12th, 2018

The grant from the National Cancer Institute, establishes a research center for advancing the understanding and treatment of small cell lung cancer. Vito Quaranta, M.D., will direct the new center.

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