Gene expression profiling has been applied to predict metastatic recurrence, the leading cause of deaths in patients with colorectal carcinoma. However, the biological mechanism is not completely understood, driving poor clinical outcomes. To address this issue, Dan Beauchamp, M.D., Bing Zhang, Ph.D., and colleagues analyzed the 11 human microarray datasets from 1,295 tumor specimens as […]
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The Lustgarten Foundation has awarded a $1.5 million Research Investigator Grant to Stephen Fesik, Ph.D., professor of Biochemistry, Pharmacology and Chemistry, for research designed to discover new drugs for the treatment of pancreatic cancer. This is Fesik’s second three-year award from the Lustgarten Foundation in support of his research targeting K-Ras, a protein mutated in […]
Prospecting for genes that might be implicated in cancer, a Vanderbilt University Medical Center research team has struck pay dirt. Zhongming Zhao, Ph.D., Peilin Jia, Ph.D., and colleagues use novel computational methods to sift through online repositories of molecular data gathered by cancer researchers worldwide. These results, and further analyses planned by the team, can […]
Two therapies already in clinical development as single agents may work in combination to treat many subtypes of melanoma, a recent study suggests.
Far more breast cancer patients are choosing to undergo mastectomy, including removal of both breasts, instead of choosing breast conservation surgery even when they have early stage disease that is confined to one breast, a Vanderbilt study shows.
A new study explaining the cellular activity that leads to breast tumor metastasis among women who have recently given birth may offer new treatment direction for postpartum breast cancer.
Vanderbilt-Ingram Cancer Center (VICC) melanoma patient Gerald (Jerry) Schreiber and wife Phyllis organized and hosted the first annual Melanoma Research Golf Classic in Evansville, Indiana. The golf scramble raised $19,000 for VICC melanoma research spearheaded by Igor Puzanov, M.D., MSCI, associate professor of Medicine and director of Melanoma Clinical Research.
A new study estimates that tobacco smoking has been linked to approximately 2 million deaths among adult men and women in Asia in recent years and predicts a rising death toll. The study, published in PLOS Medicine, was led by Wei Zheng, M.D., Ph.D., MPH, professor of Medicine and director of the Vanderbilt Epidemiology Center, […]
Scott Hiebert, Ph.D., associate director of Basic Research at Vanderbilt-Ingram Cancer Center, was celebrated for his contributions to cancer research during the 6th Annual Nashville Honors Gala benefiting the T. J. Martell Foundation. This year’s event at Nashville’s Omni Hotel honored five Nashville community leaders who work diligently to make a difference in the community, […]
Vanderbilt-Ingram Cancer Center has launched a new lung cancer screening program to provide low-dose CT scans for patients at high risk for the deadly disease. Current or former smokers ages 55 to 74 who have a history of 30 or more pack years of smoking are eligible for the scans. A pack year is defined […]