News: Leukemia

More than half of patients with relapsed multiple myeloma treated with carfilzomib experienced cardiac issues during treatment, according to a multi-institutional study published June 12 in the Journal of Clinical Oncology.

Patient Joe Lofaro credits the teamwork of Nishitha Reddy, MBBS, MSCI, and other clinicians at VUMC for diagnosing him with the rare blood cancer Erdheim-Chester disease.

Vanderbilt-Ingram Cancer Center’s Stem Cell Transplant ranks among the best in the nation for donor stem cell transplant survival rates among large centers, according to an annual report.

Vanderbilt investigators have conducted a prospective multicenter study on how extracorporeal photopheresis works in treating chronic graft-versus-host disease (cGVHD) — a complication of bone marrow or stem cell transplant that occurs when donor cells attack the recipient.

A receptor previously implicated in asthma may also play roles in other allergic diseases and in leukemia, Vanderbilt researchers have discovered.

Vanderbilt’s Pampee Young, MD, PhD, has been named chief medical officer of the American Red Cross.

Vanderbilt University Medical Center (VUMC) clinicians will host an educational symposium on bone marrow disorders, including bone marrow failure, acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), on Friday, Oct. 13, from 11:30 a.m. – 6 p.m. at the Omni Nashville Hotel, 250 5th Ave. South.

Histone deacetylases (HDACs) are enzymes that modulate gene expression and have important roles in development and disease. HDAC inhibitors are active against lymphoma, and understanding the roles of specific HDACs is important for further therapeutic development. Scott Hiebert, Ph.D., and colleagues used a mouse model to explore the role of HDAC3 in the early development […]

Acute and chronic B cell leukemia can promote T cell “exhaustion,” which contributes to increased susceptibility to infection and mortality. The treatment-independent mechanisms by which leukemia promotes T cell dysfunction are poorly understood, however. Since metabolic pathways must be tightly regulated to allow normal T cell proliferation and function, Jeffrey Rathmell, Ph.D., Peter Siska, M.D., […]

A Vanderbilt patient who has battled leukemia for nearly five years was granted a private screening of “Star Wars: The Force Awakens,” thanks to her medical providers and a local movie theater. Like millions of fans worldwide, Natalie Seale, 22, was excited to see the long-anticipated film, but she is unable to be in large […]