Radiation-induced pulmonary fibrosis — tissue scarring that can permanently impair lung function — limits the delivery of therapeutic radiation doses to non-small cell lung cancer. To develop strategies for preventing or reducing fibrosis, Michael Freeman, Ph.D., and colleagues are exploring the cell types and factors that contribute to the radiation-induced fibrotic response.
News: Lung Cancer
A simple blood test is allowing Vanderbilt University Medical Center (VUMC) researchers to determine which patients should be prescribed varenicline (Chantix) to stop smoking and which patients could do just as well, and avoid side effects, by using a nicotine patch.
Lung cancer survivors and their caregivers are invited to attend a free educational evening at Vanderbilt University Medical Center (VUMC) Thursday, Nov. 16, 5:30 – 8:30 p.m., at the University Club, 2402 Garland Ave.
Cancer investigators led by researchers at Vanderbilt-Ingram Cancer Center have co-developed a liquid biopsy blood-based assay used to identify specific gene mutations associated with the development or relapse of small-cell lung cancer (SCLC)
With the assistance of VUMC’s Outpatient Palliative Care, Nashville photographer Fred Dusel has been able to once again work on his passion — carbon transfer printmaking.
African-Americans are more likely to die from lung cancer than whites and yet few studies of possible genetic factors that contribute to this disparity have been conducted. Melinda Aldrich, Ph.D., MPH, and colleagues conducted a first-of-its-kind genome-wide association study of lung cancer survival in 286 African-Americans enrolled in the Southern Community Cohort Study. Reporting recently […]
Los Angeles native Christina Shaw had two powerful goals when she decided to move cross country to live in Nashville. The first was to support her favorite hockey team, the Nashville Predators, and the second was to meet with Leora Horn, M.D., M.Sc., a renowned lung cancer specialist at Vanderbilt-Ingram Cancer Center (VICC). Shaw, 33, […]
Under the microscope, they sparkle like emeralds, these molecules that may hold a key to understanding — and stopping — cancerous growth. The molecules are protein receptors that bind epidermal growth factor (EGF). Overexpression of the EGF receptor has been linked to multiple types of cancer. Drugs that block the receptor have become routine treatment […]
Leora Horn, M.D., M.Sc., associate professor of Medicine and clinical director of the Thoracic Oncology Program at Vanderbilt-Ingram Cancer Center (VICC), has been selected to lead a clinical research trial of combination therapy using two targeted drugs for the treatment of a specific form of lung cancer. The Phase 1/2 trial will test the drugs […]
Researchers in the Schools of Medicine and Engineering at Vanderbilt University have discovered a proteomic “signature” from the airways of heavy smokers that could lead to better risk assessment and perhaps new ways to stop lung cancer before it starts. Their findings, reported recently in the journal JCI Insight, are based on the observation that […]