Somatic mutations, which can occur in any cell except sperm or egg, are not inheritable. Several recent studies have demonstrated that disease-causing mutations commonly alter protein folding, protein stability and protein-protein interactions. It has been difficult, however, to determine which somatic mutations identified in tumor samples “drive” the cancer development and which are just “along […]
News: Lung Cancer
FDG-PET technology is less accurate in diagnosing lung cancer versus benign disease in regions where infections like histoplasmosis or tuberculosis are common, a recent study has found.
Joe B. (Bill) Putnam Jr., M.D., Ingram Professor of Cancer Research and chair of the Department of Thoracic Surgery, and colleague Felix Fernandez, M.D., assistant professor of Surgery, Emory University School of Medicine, Atlanta, have received a grant to investigate the most effective forms of surgery to treat lung cancer patients.
Lung cancer patients with specific gene alterations may benefit from combination therapy that targets two different cancer pathways, a recent study suggests.
A new study estimates that tobacco smoking has been linked to approximately 2 million deaths among adult men and women in Asia in recent years and predicts a rising death toll. The study, published in PLOS Medicine, was led by Wei Zheng, M.D., Ph.D., MPH, professor of Medicine and director of the Vanderbilt Epidemiology Center, […]
Vanderbilt-Ingram Cancer Center has launched a new lung cancer screening program to provide low-dose CT scans for patients at high risk for the deadly disease. Current or former smokers ages 55 to 74 who have a history of 30 or more pack years of smoking are eligible for the scans. A pack year is defined […]
Christine Lovly, M.D., Ph.D., instructor in Medicine at the Vanderbilt University School of Medicine, has earned the 2013 Damon Runyon Clinical Investigator Award, which supports young physician-scientists conducting patient-oriented cancer research. The three-year award will provide $450,000 for Lovly’s research efforts in lung cancer. “I am so honored to receive this prestigious and competitive award […]
By Dagny Stuart A study led by Vanderbilt University Medical Center investigators found that rates of benign lung disease diagnosis varied widely by state following surgery for lung cancer. The results could have an impact on clinical guidelines and health policy for lung cancer screening. The study was presented by Stephen A. Deppen, M.A., M.S., […]
More Tennesseans are expected to die this year from lung cancer than any other form of cancer. Yet, lung cancer research receives far less funding than other forms of the disease. To address this funding disparity, the LUNGevity Foundation will host the second annual Breathe Deep 5-K race/walk event, Saturday, Nov. 17, in Nashville’s Centennial […]
Caroline Nebhan, right, a fourth-year student in the M.D./Ph.D. training program, explains a cancer research experiment to advocates from the National Lung Cancer Partnership who toured Vanderbilt-Ingram Cancer Center during their recent meeting in Nashville. Nebhan, who works in the research laboratory of William Pao, M.D., Ph.D., is studying the effects of a specific cancer […]