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    News: Wnt pathway

    Colon Cancer’s Cellular Crossroads

    Friday, March 16th, 2012

    Colon cancer development and progression involves alterations in several cell signaling pathways. Activation of the Wnt pathway is involved in the early stages of tumor development, while inactivation of signaling through the TGF-beta pathway (which typically suppresses tumor formation) is involved in later stages. However, the interactions between these pathways remain unclear. R. Daniel Beauchamp, […]